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While the acute natriuretic effect of GLP-1 has been solidly confirmed in humans [[762], [763], [764]], 12 wk treatment of T2DM patients with liraglutide or the DPP-4 inhibitor sitagliptin had no effect on markers of renal function, including glomerular filtration rate, renal plasma flow, albumin-to-creatine ratio, and excretion of sodium, potassium, and urea [765]