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Akt is activated as a result of insulin or insulin growth factor signaling and plays a vital role in GLUT4 translocation 20
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Clinical Evidence In a 2021 clinical trial (SURPASS-2), tirzepatide was found to have greater reductions in hemoglobin A1c (HbA1c) and body weight than semaglutide 1 mg in people with type 2 diabetes [6]
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