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When Eli Lilly’s tirzepatide, a dual agonist that targets both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors was evaluated in the SURMOUNT-1 trial, participants lost an average of 22.5% of body weight at the highest dose
GLP-1 Receptor Agonist
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Preclinical research has shown that GLP-1RAs can decelerate the development and progression of atherosclerotic lesions by stabilizing and reducing plaque vulnerability (24)
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