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The peptide CDMO market, valued at approximately $4.14 billion in 2025, is forecast to reach $9.84 billion by 2031 at a compound annual growth rate of 15.5%
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This heightened sympathetic activation leads to excessive norepinephrine (NE) release, primarily acting on cardiac β1-adrenergic receptors to activate Gs protein signaling, stimulate adenylyl cyclase, and elevate intracellular cyclic adenosine monophosphate (cAMP) [39]
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