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Among patients not taking a sulfonylurea, blood glucose less than 54 mg/dL with or without symptoms occurred in 22 (7.1%) of 312 SAXENDA-treated patients and 7 (4.5%) of 157 placebo-treated patients
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Given the limited efficacy and potential metabolic consequences of brief drug interruptions, discontinuation for ≥7 days should be restricted to cases of proven preparation failure despite intensified regimens or to those manifesting florid upper gastrointestinal symptoms
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