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Comparison of body weight parameters for semaglutide versus placebo... | Download Scientific Diagram
Sarcopenia can contribute to the onset of T2D by reducing skeletal muscle mass, a major site for insulin-mediated glucose disposal, while sarcopenia is also associated with physical inactivity and frailty, both risk factors for T2D [73,74,75]
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The observation that IV GLP-1 leads to a reduction in plasma glucose after a meal in individuals with T2D, while a rise in plasma glucose was observed after subsequent meals (18), suggested there may be tachyphylaxis for the effects of GLP-1 to slow gastric emptying
