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Study: US obesity rates are dropping as GLP-1 use increases

This can create a self-reinforcing cycle — sometimes described as a “metabolic doom loop” — where insulin resistance leads to further fat mobilisation and ongoing metabolic disruption

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Novel insights into GIP receptor targeting treatment reveal that both GIP receptor antagonists and agonists, when combined with glucagon like peptide 1 (GLP-1) receptor activation, are associated with improved glycemic control and weight loss