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“When FDA-approved drugs are available, outsourcing facilities cannot lawfully compound using bulk drug substances unless there is a clear clinical need,” said FDA Commissioner Marty Makary, M.D., M.P.H

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Oral GLP-1s can produce an average weight loss of ~6%–14%, depending on the medication: Rybelsus (semaglutide) produces nearly 6% weight loss in one year , according to a small study of adults with obesity