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Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action: Cell Metabolism
doi: 10.1042/BCJ20170736
Med
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To investigate whether QMP would secure a long plasma half-life of a GLP-1 albumin fusion, we constructed a recombinant fusion protein with the identical amino acid sequence as Tanzeum (albiglutide-mimic: GLP-1 WT), as well as a modified version containing the QMP substitutions (GLP-1 QMP) (Fig