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No planned short off-cycle phase Neither Phase 2 trial was designed around a repeating short cycle such as 8 weeks on and 8 weeks off
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GLP-1RAs improve glucose uptake in cardiomyocytes through dual mechanisms: triggering AMPK activation to facilitate GLUT4 translocation to the cell membrane and regulating the insulin signaling pathway to upregulate GLUT4 expression (79, 80)
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