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A report published in January 2025 by the US Office of Inspector General identified significant flaws in accelerated approval processes for three drugs (Biogen’s Aduhelm/aducanumab, Sarepta’s Exondys/eteplirsen, and Covis Pharma Group’s Makena/hydroxyprogesterone caproate), raising questions over the effectiveness and consistency of the fast track pathway
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Cząsteczka to łańcuch 39 aminokwasów z acylacją łańcuchem kwasu tłuszczowego, ma masę około 4813,5 g/mol, a jej długi okres półtrwania (wiązanie albuminy) stanowi podstawę tygodniowego schematu w badaniach nad odpowiednikiem leczniczym