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1 If you notice these symptoms, get in touch with your doctor as soon as possible because they could be life-threatening
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Contact your GP, call NHS 111, or seek urgent care if you notice : Significant swelling, warmth, or redness spreading beyond the injection site Signs of infection, such as pus, increasing pain, or fever A hard, painful lump that does not resolve within a few weeks Severe or persistent abdominal pain, with or without vomiting — seek urgent medical assessment, as this may require evaluation for serious conditions such as pancreatitis An allergic reaction, including rash, difficulty breathing, or swelling of the face or throat — this requires immediate emergency care (call 999) Beyond local reactions, retatrutide — like other agents in its class — may cause systemic gastrointestinal side effects such as nausea, vomiting, and diarrhoea, particularly during dose escalation