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Week 8 Check-In: First Refeed in 3 Weeks + Retatrutide Update
Two Convenient Options: Injections or Oral Drops EllieMD’s GLP-1 and GLP-1/GIP peptide therapies are available in both injectable and oral formulations, allowing you to choose the method that best fits your preferences
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Pathophysiologic Context In PAH + HFpEF overlap: * ET‑A receptors drive vasoconstriction, hypertrophy, and fibrosis * ET‑B receptors mediate endothelin clearance, nitric oxide release, and natriuresis * HFpEF patients rely on ET‑B signaling to maintain volume balance and endothelial function Blocking ET‑B in HFpEF increases the risk of fluid retention and rising left‑sided filling pressures
