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Locally in the gastrointestinal tract, they delay gastric emptying by reducing antral and duodenal motility while increasing pyloric tightening
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Obstructive Sleep Apnea Obstructive sleep apnea (OSA) is characterized by recurrent partial or complete upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation.[44] Obesity is a major risk factor for OSA, prompting investigation into whether GLP-1RAs could serve as a therapeutic option.[44] Clinical studies have shown that liraglutide reduces the apnea-hypopnea index (AHI) in patients with OSA
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