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Liraglutide, semaglutide and dulaglutide are – except for few modifications – highly similar to the structure of human GLP-1, while exenatide and lixisenatide are based on exendin-4, a naturally occurring peptide derived from the saliva of the Gila monster, and only share around 50% homology with the human GLP-1 molecule

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” Am J Cardiovasc Drugs