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Based on the above pharmacological characteristics of categories of GLP-1RAs agents, despite slight adverse gastrointestinal side effects, it is clear that GLP-1RAs agents have efficacy in cardiovascular protection without untoward hypoglycemia

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Patents will reshape the landscape: semaglutide loses composition-of-matter exclusivity in 2031, while tirzepatide extends to 2036, creating different windows for biosimilar entry