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Average body weight reduction at 68 weeks in the STEP 1 trial alongside lifestyle intervention

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Embodiment 2 [0105] On the basis of Example 1, the condensing agent used when coupling Boc-His(Trt)-Aib-OH was replaced by TBTU / DIEA, and the obtained semaglutide crude peptide HPLC detection results were as follows Figure 5 As shown, the purity of semaglutide is 72.088%, and the maximum purity is 6.843%