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On December 20th, the FDA approved Eli Lilly’s Zepbound® (tirzepatide) for the treatment of moderate-to-severe OSA in adults with obesity ( The SURMOUNT-OSA clinical trial assessed the efficacy of tirzepatide independently from CPAP therapy among a small subset of the total OSA population and does not compare the efficacy of tirzepatide to CPAP therapy in treating OSA

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True pathological hypercortisolism (Cushing's syndrome) is typically caused by endogenous ACTH excess, adrenal disease, or exogenous glucocorticoid medication use , rather than by chronic psychological stress alone