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semaglutide 2.4 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial such as high blood pressure

GLP-1 receptor activation also decreases inflammation and fibrosis in the liver through suppressing the release of inflammatory cytokines and dampening inflammasome activation

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GLP-1 Receptor Agonists and Neurological Protection Beyond Weight Loss Semaglutide and other GLP-1 medications work by activating receptors throughout the body, including in areas of the brain involved in appetite regulation and pain processing