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Cardinal symptoms of gastroparesis include persistent nausea, recurrent vomiting (particularly of undigested food consumed hours earlier), early satiety, postprandial fullness, bloating, and upper abdominal discomfort
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The binding of incretins to GPCRs triggers a cascade of intracellular events, including cyclic AMP production and the consequent activation of protein kinase A
![PDF] Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial](https://figures.semanticscholar.org/7fe85daed4f884830ea71a1fe88205a43e1c1a7f/4-Table1-1.png)
