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Histopathological evaluation demonstrated a reduced expression of inflammatory cytokines, such as IL-17, IL-23, and TNF, in the psoriatic skin of patients receiving liraglutide, suggesting a potential link to skin lesion improvement [148]
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Functional MRI studies investigating the effects of intranasal insulin administration have revealed that insulin can modulate activity in brain regions involved in mood regulation, such as the prefrontal cortex and hypothalamus
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