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Precision is also paramount in terms of getting optimal treatment for people, and the appeal of different treatments might differ amongst people.” GLP-1 Treatments Face Hurdles While GLP-1s offer promising benefits for some patients, significant barriers remain regarding supply, cost, and insurance coverage—challenges that Saunders describes as “humongous limitations.” Novo Nordisk’s Ozempic and Wegovy have been on the FDA’s drug shortage list since 2022