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Among GLP-1 RA users, only 5% were prescribed semaglutide in 2018, while in 2023 this number rose to 63%
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GLP-1 RAs have been shown to promote the expression of brain-derived neurotrophic factor (BDNF), enhancing synaptic plasticity and neurogenesis, particularly in the hippocampus and prefrontal cortex [84]
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