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In January 2016, Judge Saylor ruled to allow more than 200 Zofran lawsuits to proceed, rejecting GSK’s arguments for dismissal based on federal preemption — i.e., that plaintiffs’ claims regarding GSK’s warning labels were based on state laws, which are preempted by federal law, under which the FDA would not have permitted GSK to modify the labels the way plaintiffs claimed was appropriate
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From 2008-2010, Sanofi-Aventis’ Acomplia (selective CB1 antagonist) and Abbott Laboratories’ Meridia (NE/5-HT reuptake inhibitor)--both also designed to suppress appetite--were pulled from the market over similar cardiac safety concerns
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