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- Participants in the semaglutide group achieved a weight loss of at least 5%, 10%, or 15%, and improvements in secondary endpoints, such as waist circumference, blood pressure, and lipid levels, compared to the placebo group
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BACKGROUND Obesity disease is an increasing public health challenge in Japan, where it is defined as body mass index (BMI) โฅ25 kg/mยฒ and is associated with a substantial burden of obesity-related comorbidities, including type 2 diabetes (T2D), cardiovascular disease (CVD), and impaired quality of life
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