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FDA trials show semaglutide produces 5-15% body weight reduction on average regardless of starting weight, with results driven by BMI reduction rather than absolute pounds lost
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Topline results from the ESSENCE trial demonstrated that 62.7% of patients who received once-weekly Wegovy 2.4 mg SC had improved steatohepatitis and 37% had improved liver fibrosis compared 34.1% and 22.5%, respectively, of patients who received placebo
