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A subgroup of the patients had functional MRI (fMRI) and single‐photon emission CT (SPECT) scans performed at baseline and after 26 weeks of treatment, to investigate potential neurobiological changes (the clinical study has been completed, and the manuscript is in preparation, ClinicalTrials.gov identifier NCT03232112) (Antonsen et al., 2018)
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To establish the functional significance of these findings, we next tested the ability of GLP-1(28–36) to prevent cytotoxicity in an in vitro model of oxidative stress (38)
