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Understanding GLP-1 agonists: benefits, uses and side effects | UnitedHealthcare

Eur J Endocrinol (2002) 146:241–4.10.1530/eje.0.1460241 36 BroglioFArvatEBensoAGotteroCMuccioliGPapottiMet alGhrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans

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Combination therapies such as Qsymia or the generic phentermine plus topiramate regimen also use stepwise increases to ensure tolerability