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Although generally well tolerated, semaglutide should not be taken by certain individuals: Anyone allergic to semaglutide or any inactive ingredients in the product Those with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Women who are pregnant or planning pregnancy (stop semaglutide at least 2 months before conception) Breastfeeding women (discuss risks if taking Wegovy or Ozempic